[Focus on systemic sclerosis].

Dtsch Med Wochenschr 2026 Jun; 151(12):645-651.DM

Systemic sclerosis is one of the most challenging autoimmune connective tissue diseases. 2024 new treatment recommendations were published by EULAR which now are amended by German recommendations for diagnostic and therapy. This overview article focuses on these new advices to help referring physicians to identify patients with typical clinical features earlier and thus to improve early diagnosis and future treatment options. Here, especially (but not solely) B-cell targeting therapies are in the scope.